Armando Alvarez (Will Ferrell) has lived and worked on his father's ranch in Mexico his entire life. As the ranch encounters financial difficulties, Armando's younger brother Raul (Diego Luna), shows up with his new fiancé, Sonia (Genesis Rodriguez). It seems that Raul's success as an international businessman means the ranch's troubles are over as he pledges to settle all debts his father has incurred. But when Armando falls for Sonia, and Raul's business dealings turn out to be less than legit, all hell breaks loose as they find themselves in a war with Mexico's most feared drug lord, the mighty Onza (Gael Garcia Bernal).

In Korea Town Los Angeles, a young man, Kengo, believes he's the son of God - that's what his mother told him since he was a young boy. He spends his days working his dead-end job and figuring out his complex feelings for his girlfriend until, one day, he sees a one-eared man who could be his father and decides to follow him around Los Angeles.